![]() ![]() Question: We are struggling with what type of “emergency administration” we would want to sanction. Practice guidelines for postanesthetic care: An updated report by the American Society of Anesthesiologists Task Force on Postanesthetic Care. Apfelbaum JL, Silverstein JH, Chung FF, et al.Practice guidelines for sedation and analgesia by non-anesthesiologists. American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists.Antidotes for toxicological emergencies: a practical review. 2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. 1-4 The American Society of Anesthesiologists still recommend that antidotes which reverse opioids and benzodiazepines be readily available during moderate and deep sedation. While there may be a limited role for flumazenil in acute overdose, it is still administered in select patients to reverse excessive sedation and respiratory depression as a result of benzodiazepine use during procedural sedation. ![]() Why do you recommend it?Īnswer: Flumazenil in this case is used only as an example, and it is the responsibility of each individual hospital to decide which antidotes should be made readily available for use. There is evidence in the literature that recommends against the use of flumazenil for the treatment of benzodiazepine overdose (Am J Health-Syst Pharm. ![]() Question: I noticed that as an example of an antidote in Best Practice 9, flumazenil is recommended to counteract the effects of benzodiazepines. Have directions for use/administration readily available in all clinical areas where the antidotes, reversal agents, and rescue agents are used.ġ. Have standardized protocols and/or coupled order sets in place that permit the emergency administration of all appropriate antidotes, reversal agents, and rescue agents used in the facility. ![]() Best Practice #9: Ensure all appropriate antidotes, reversal agents, and rescue agents are readily available. ![]()
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